Macroglossia and Edema—What Do You Suspect?

A 65-year-old male presents to his family physician with complaints of increasing fatigue, dyspnea on exertion, and unintentional weight loss within the last six months. On examination, he is noted to have macroglossia and peripheral edema. Crackles are audible bilaterally on chest auscultation. Which of the following tests will help to confirm this patient’s most likely diagnosis?

A. Bone marrow biopsy
B. Coronary angiography
C. Pulmonary function tests
D. Thyroid function test

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Discussion