I was interviewed by a neuroscientist and I have done research in neurology so I was asked a lot of specific questions about my research. I think Downstate tries to match people with the interviewer so make sure you are very knowledgeable about everything you claim to be knowledgeable about!
What were you like in high school? First question I was asked, wasn't expecting it and totally threw me off. I couldn't even remember what I was like in high school and babbled through the first awkward minutes of the interview.